Conversion of THP Ethers. The use of 0.2 eq. of TiCl 4 and 1.2 eq. of Ac 2 O enables a mild direct conversion of THP ethers to acetates. S. Chandrasekhar, T. Ramachandar, M. V. Reddy, M. Takhi, J. Org. Chem., 2000, 65, 4729-4731. An efficient and user-friendly procedure has been developed for the oxidative deprotection of tetrahydropyranyl (THP) ethers with N-bromosuccinimide (NBS) using β
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Full-scan product ion chromatogram of a real plasma sample at 1 h after JLZS administration is shown in Figure 4 C. It can be seen that seven components (THP, THC, THB, COR, PAL, DHC, and TSN) were absorbed into the blood of rats, while other compounds with weaker membrane permeability were not absorbed.
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WhatsAppGet PriceGet A QuoteFor instance, SSG was inactive in the infections of BMDM and THP-1 using promastigote form (>1000 µM), but became active in amastigotes infections with EC 50 = 98.8 µM for THP-1 and 638 µM for BMDM (Figure 6C). Interestingly, SSG susceptibility was mostly active in systems in which PVs were observed.
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WhatsAppGet PriceGet A QuoteTHP-1 is a human leukemia monocytic cell line, which has been extensively used to study monocyte/macrophage functions, mechanisms, signaling pathways, and nutrient and drug transport. This cell line has become a common model to estimate modulation of monocyte and macrophage activities. This review a …
WhatsAppGet PriceGet A QuoteTHP-1 cells were cultured in RPMI 1640 media with L-glutamine supplemented with 10% fetal bovine serum, 100 units/ml penicillin, 100 μg/ml streptomycin. THP-1 cells were differentiated into macrophage cells using PMA (150 nM) overnight. The PMA was removed and cells were used for experiments 24 h later.
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